Antioch on the Orontes (/ˈænti.ɒk/; Ancient Greek: Ἀντιόχεια ἡ ἐπὶ Ὀρόντου, romanized: Antiókheia hē epì Oróntou, pronounced [anti.ó.kʰeː.a])^{[note 1]} was a Hellenistic Greek city^[1][2] founded by Seleucus I Nicator in 300 BC.^[3] It was one of the greatest and most important Greek cities of the Hellenistic period.^[2] The city served as the capital of the Seleucid Empire and later as regional capital to both the Roman and Byzantine Empire. During the Crusades, Antioch served as the capital of the Principality of Antioch, one of four Crusader states that were founded in the Levant. Its inhabitants were known as Antiochenes. The modern city of Antakya, in Hatay Province of Turkey, was named after the ancient city, which lies in ruins on the Orontes River and did not overlap in habitation with the modern city.